St. Mary’s College of Meycauayan, formerly called Escuela Catolica de Meycauayan and St. Mary's Academy of Meycauayan , was founded in 1916 as a Parochial School offering the primary course with Catechism as its core subject. It was and is still managed and administered by the Religious of the Virgin Mary (RVM), the first Filipino Congregation founded in 1684 by a Filipina, Mother Ignacia del Espiritu Santo. During the Second World War, classes were temporarily suspended in June 1944 and were reopened in July 1945 with the Intermediate and First Year High School classes. March 1949 marked the graduation of the first ten High School seniors of the then St. Mary’s Academy.